Case Study #3: Alexion Challenge

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases through the discovery, development and commercialization of life-changing therapies.

Since its founding in 1992, Alexion has given hope to people who had none and shined a light on those who felt isolated and alone. But we know that fighting rare diseases takes so much more than hope. It requires persistence, dedication, and a relentless pursuit of the highest levels of medical innovation. At Alexion, our goal is to deliver medical breakthroughs where none currently exist. We are driven because we know people’s lives are at stake.

Through the transformative power of our science, Alexion has delivered life-changing therapies to patients suffering from rare diseases. We have pioneered the complex field of complement biology and delivered solutions to challenges that once seemed impossible for patients with devastating complement-mediated and metabolic disorders.

The Alexion Challenge:

Can you follow the money in healthcare to identify opportunities for investment and areas of over spending? Who are the winners and losers in healthcare funding?

The challenge can be broken into two parts – one which looks at the research spend only and the second, which uses a combination of the payment and the research spend data (select the latter option if you are comfortable working with large data sets).

Your analysis should address one or more of the following questions:

  • Where are the research dollars and or money overall flowing in healthcare?
    • Can you find common factors by analyzing the type of drug, device, company, hospital, or therapeutics?
  • Are there demographic or geographic patterns?
    • Can you identify areas of concern or gaps in healthcare research spending?
  • How do the overheard costs such as entertainment compare to research costs?
    • Which diseases are being ignored?
    • Which physician specialties are the most and least popular in terms of investment and what implications does that have for the future?

Datasets

Click here for Alexion Data

  • Be certain to view the PDF file named Alexion_2018_analytics _challenge for detailed information about the datasets and other reference materials.

Other Rules

  • The project submissions must entirely be the work of the project team. While faculty and other individuals can help review the submission, they should not contribute to the content of the report or the solution.
  • Incomplete submissions will not be considered, so make sure you have all of your submission deliverables are in the submission package.
  • The contest materials must be submitted by the due dates. Late submissions will not be accepted and no extensions will be given.
  • Submission Instructions

    What you should submit

    • A case study file will be submitted as a Word document: The case study is expected to have various figures and graphics (See the resources for creating infographics and case study). Refer to the Resources section for access to resources for creating info graphics and case studies.
    • Participants are encouraged to use data to present tables, to present their arguments. (See the resources for data and visualization).Refer to the Resources section for access to resources for data and visualization.
    • The Word file should be between 5-15 pages long (not including references or appendix).
    • The file should specify the names of the participants as well as the topic chosen. See the details of the topics and more resources about the topic at computational society resource pages http://thecomsociety.com/pages/computationalsocietychallenge2019home
    • A cover letter in the format found at http://thecomsociety.com/assets/competitionPDFs/Sample_TCS_2019_Email_Template.pdf

    How you should submit

    • Inform about the intent to participate in the competition as soon as possible by writing to competitions@thecomsociety.com
    • Register after you are provided access to the website (you will receive this as a reply to your intent to participate request) at www.thecomsociety.com. The membership will be upgraded to a premium membership after registration for no additional fee.
    • Email your entry to competitions@thecomsociety.com by 11:59 p.m. U.S. Eastern Time, March 1, 2019.

    What happens after you submit

    • You will receive a confirmation email acknowledging your entry.
    • Finalists will be notified by email after March 1, 2019.
    • Finalists will present their work in front of the judging panel at the AIS SCLC April 11-13, 2019. See the page on The Computational Society website for details of prizes and awards. Visit www.thecomsociety.com or contact competitions@thecomsociety.com for details.
  • Timeline

    All preliminary submissions must be recieved no later than March 1, 2o20
    Finalists will be announced after March 1, 2020
    The winner will be revealed at the Student Chapters Leadership Conference between April 11 – 13, 2020

  • Prizes

    Entrants to the 2019 Computational Society Case Challenge will be competing with AIS and non-AIS student chapter teams and individuals across the globe, in Stage 1. Non-AIS members will be awarded based on their Stage 1 performance. The top AIS-affiliated teams and individuals from Stage 1 of the competition will move forward to compete at the 2019 AIS Student Chapter Leadership Conference in Philadelphia April 11-13. Stage 2 is exclusively for AIS student chapter teams and individuals* selected as finalist in Stage 1. AIS Stage 1 finalist will then compete for top prizes in Philadelphia. Submissions to all case studies are judged collectively and prizes are awarded to the top 3 cases regardless of the selected case scenario: (1) Retail Analytics and Automation of Choice, or (2) AI and Analytics to Unravel Individual Choice, or (3) Artificial Intelligence (AI), Computational technologies, and well-being!

    Monetary Prizes, based on Stage 1 performance

    First place – $250
    Second place – $150
    Third place – $100

    Monetary Prizes, based on Stage 2 performance

    First place – $2,000
    Second place – $1,000
    Third place – $500

    Other Prizes

    • Certificates: All finalists are given certificates indicating their rank.

    *To compete as an AIS team or individual, you must be an officially recognized chapter or a member of an officially recognized chapter. Forming an AIS Student Chapter at your institution is easy, but can take as much 6-8 weeks to complete the process depending on your university policy and procedures so get started today. For more information on how you can start a chapter, contact Dr. Rhonda Syler, AIS Vice President for Student Chapters, at studentchapters@aisnet.org.

  • Questions

Judging

How entries will be evaluated

All entries will be evaluated by the judges in two categories: visualization and analysis. The finals will also be judged by industry professionals.

The specific criteria for each category are:

Graphic

  • Clarity (how well the graphic stands on its own without additional explanation)
  • Novelty/creativity (originality of thought; surprising way of approaching the data)
  • Insight (graphic aids understanding of the data)
  • Utility (ability of the graphic to aid decision making)

Analysis

  • Relevance (analysis relates to the problem statement)
  • Completeness (degree to which the analysis answers the stated question)
  • Depth (sophistication of the analysis)
  • Consistency (conclusions consistent with the analysis)

Your entry will be disqualified if…

  • It is submitted after the deadline.
  • The attachments won’t open or are in the wrong file format.
  • Your interactive graphic won’t run.
  • You don’t specify the challenge you are addressing.
  • Team member names and college name are not on both the graphic and the description.